Okoznak a diuretikumok hyperparathyreosist? Virányos Klinika, Budapest Prof. Dr. Radó János főorvos
OKOZNAK A DIURETIKUMOK HYPERPARATHREOSIST? OKOZNAK A DIURETIKUMOK HYPERPARATHREOSIST? Radó János 2
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A FUROSEMID HATÁSA A PARATHORMONRA NORMÁL EGYÉNEKBEN 6
Risk factors for secondary hyperparathyroidism in a nursing home population Vitamin D deficiency is a common risk factor for secondary hyperparathyroidism in nursing home residents. However, the daily frusemide dose is a more important predictor of PTH in this population. Risk factors for secondary hyperparathyroidism in a nursing home population Mark S. Stein, Samuel C. Scherer, S. Lynette Walton, Richard E. Gilbert,Peter R. Ebeling,Leon Flicker, John D. Wark Article first published online: 26 NOV 2003DOI: /j x Clinical Endocrinology 44:pages 375–383, April 1996 Vitamin D deficiency is a common risk factor for secondary hyperparathyroidism in nursing home residents. However, the daily frusemide dose is a more important predictor of PTH in this population. 7
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FUROSEMID TETANIA
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18 ACTIONS OF FRUSEMIDE AND A THIAZIDE, THE LANCET AUGUST 26,1967
19 FSD + TIAZID EGYÜTT HATÁSOSABB, MINT SZÁMITVA VÁRHATÓ LENNE egészséges egyénekben maximális vizdiuresis alatt osmolalis clearance-ben mérve Radó J, Szende L, Takó J, Borbély L: Further studies on the site of action of clopamide and furosemide. J Clin Pharmacol New Drugs 1969;9:99.
20 H Y G R O T O N +FSD +BB+CaB+ACEI+ARB KVE-ben eGFR ml/min /18 hó
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22 KÖVETKEZTETÉS I.
23 KÖVETKEZTETÉS II.
KÖVETKEZTETÉS III. 24
Urine calcium, Urine calcium, mg/day No diuretics 39,6 Loop 55 Thiazide 25,5 Loop- thiazide 30.3 Loop- thiazide 30.3 (NDT March 7, 2011) 25